Estimating the Usual Iodine Intake From Spot Urinary Iodine Concentrations to Obtain the Prevalence of Inadequate or Excess Iodine Intake in School-aged Children and Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,592
- 试验地点
- 2
- 主要终点
- Estimated iodine intake
研究概览
简要总结
The overall objective of this study is to develop a reliable method to obtain habitual iodine intakes from spot urinary iodine concentration (UIC) and to assess the prevalence of inadequate iodine intake in school-age children and women of reproductive age. We will evaluate different methods to estimate iodine intake from UIC and estimate the prevalence of inadequate and excess iodine intake in UIC studies conducted in populations with low, adequate and high iodine intakes using the the established estimated average requirement (EAR)/Tolerable Upper Intake Level (UL) cut-point method.
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 9 Years 至 13 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •lived in study area >= 12 months
- •no reported intake of Amiodarone
- •no history of thyroid dysfunction / goiter (past & present)
- •no exposure to iodine containing contrast agents within the last 12 months
- •Second arm: Women aged 18 - 49, exclusion / inclusion criteria apply, plus non-pregnant, non-lactating.
排除标准
- 未提供
结局指标
主要结局
Estimated iodine intake
时间窗: 17 months
Estimated daily iodine intake of the study population derived from urinary iodine and creatinine concentrations measured in spot urine samples
次要结局
- Urinary creatinine concentration(17 months)
- Urinary iodine concentration(17 months)
研究者
Maria Andersson
Dr.
Swiss Federal Institute of Technology