Performance in Walking in Osteoarthritis Patients: the Role of Fatigue and the Effect of an Eccentric Muscle Building Program
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Walking performance
研究概览
简要总结
Few data exist to date on the effect of eccentric muscle building in knee osteoarthritis. No studies have compared the effect of eccentric versus concentric reinforcement in knee osteoarthritis. Our study aims to show the effectiveness of an eccentric reinforcement. This is a randomized, interventional trial.
详细描述
Few data exist to date on the effect of eccentric muscle building in knee osteoarthritis. No studies have compared the effect of eccentric versus concentric reinforcement in knee osteoarthritis. Our study aims to show the effectiveness of an eccentric reinforcement, the interest of a work supervised by a sports coach to maintain activity over time and to study the effect of this activity at the muscular level. The main objective is to study the effect of an eccentric muscle strengthening program on walking performance in osteoarthritis patients. The secondary objectives are to study: the effect of fatigue on walking, the relationship between fatigue and the level of physical activity, the effect of training on perceived fatigue and the effect of training on the function and at muscular level. This is a randomized, interventional trial. 40 subjects are planned. Inclusion criteria include: age 40-85 years, KL 2 and 3. The subjects are divided into two groups to perform either eccentric or concentric work. 2 sessions per week for 6 weeks. At baseline and at the end of the study a clinical evaluation and MRI will be carried out for evaluation of the criteria of judgment
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Autonomous subjects aged 40 to 85
- •Subjects meeting ACR criteria for gonarthrosis
- •Subjects with a score of Kellgren and Lawrence at least one knee greater than or equal to 2
- •Signature of consent form
- •Subjects affiliated to social security
排除标准
- •Subject with a Kellgren and Lawrence stadium at 4 for at least one of his two knees
- •Subjects with symptomatic femoro-patellar arthrosis
- •Subject with a pathology that makes walking testing impossible.
- •Non-autonomous subjects, with a pathology impairing walking
- •Subjects with symptomatic osteoarthritis of the hip and / or with a hip or knee prosthesis
- •Subject incapable of signing consent and unable to understand information leaflet.
研究组 & 干预措施
concentric work
patient suffering from knee osteoarthritis will follow a concentric work. This training is 2 sessions per week for 6 weeks
干预措施: concentric work (Other)
eccentric work
patient suffering from knee osteoarthritis will follow an eccentric work. This training is 2 sessions per week for 6 weeks
干预措施: eccentric work (Other)
结局指标
主要结局
Walking performance
时间窗: after 6 training weeks
6-minute walk test
次要结局
未报告次要终点