NCT02827422Unknown不适用
A Prospective, Multicenter Registry With Targeted Temperature Management After Out-of-hospital Cardiac Arrest in Korea
Kyu Nam Park1 个研究点 分布在 1 个国家目标入组 1,800 人开始时间: 2015年10月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,800
- 试验地点
- 1
- 主要终点
- survival
研究概览
简要总结
Therapeutic hypothermia after out-of-hospital cardiac arrest is considered as a standard care. However, optimal candidates, optimal dose, duration, timing of initiation and rate of rewarming is still unknown. The objective of this project is to improve the outcomes for patients after resuscitation from out-of-hospital cardiac arrest treated with therapeutic hypothermia established from the analysis of multicenter registry data.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age of older than 18 years
- •out-of-hospital cardiac arrest
- •comatose mentality after return of spontaneous circulation (ROSC)
- •treated with therapeutic hypothermia, regardless of target temperature
排除标准
- •suspected or confirmed to cerebrovascular accident
- •poor pre-arrest neurologic status (CPC>3)
- •patients who are terminally ill or for whom intensive care dose not seem to be appropriate
- •Do not attempt resuscitation (DNAR) order
- •patients with tympanic membrane temperature below 30 degree celsius on admission
结局指标
主要结局
survival
时间窗: 6 months after cardiac arrest
Neurologic Outcome
时间窗: after 6 months
modified Rankin Scale (mRS) mRS 0,1,2, 3 : Good Outcome mRS 4,5,6 : Poor Outcome
次要结局
- survival(duration of hospitalization, limit 180 days)
- neurological outcome(1 month after cardiac arrest)
- Survival(1 month after cardiac arrest)
研究者
Kyu Nam Park
Professor
Seoul St. Mary's Hospital
研究点 (1)
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