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临床试验/NCT06090032
NCT06090032尚未招募不适用

Copmined Sono-pulmonary Score and APACHE Score as a Predictor of Outcome in Respiratory Intensive Care Unit Patients With Ventilator Associated Pneumonia

Assiut University0 个研究点目标入组 53 人开始时间: 2023年11月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
53
主要终点
Compined SONOPULMONARY infection score and APACHE score as a predictor of outcome in RICU patients with ventilator associated pneumonia

研究概览

简要总结

Aim of the study :

  1. Efficacy of Sono pulmonary infection score in combination with APACHE score in early diagnosis of VAP
  2. Assessment of prediction role of combined SIPS SCORE and APACHE SCORE of outcome of VAP patient in RICU
  3. Assessments of role of ultrasonography in early diagnosis and follow up of VAP

详细描述

Pneumonia is a bacterial, viral or fungal infection of the lungs, which causes the alveoli of the lungs to fill up with microorganisms, fluid and inflammatory cells, preventing the lungs from functioning effectively[1]. Ventilator associated pneumonia (VAP) is the most common and a leading cause of death in intensive care unit patient. Ventilator associated pneumonia is caused by prolonged duration of mechanical ventilation ,and prolonged hospital stay, which increase hospital costs, possibly increase mortality rate, and increase antibiotic use in ICU patients , early identification of VAP is an important clinical goal to improve patient outcomes [2]. In recent year several scoring systems have been developed to evaluate the severity of illness and to predict the outcome, especially the mortality rate of intensive care unit patient, such as the Clinical pulmonary infection score (CPIS) or modified (CPIS)The Clinical Pulmonary Infection Score (CPIS) was developed to serves a tool to facilitate the diagnosis of ventilator-associated pneumonia (VAP),The CPIS is calculated on the basis of points assigned for various signs and symptoms of pneumonia (eg, fever and extent of oxygenation mpairment) ,a CPIS has an average between 0-12>6 some studies suggest that CPIS >6 may correlate with VAP Sonar is easy bedside test to diagnose pleural effusion, pneumonia pneumothorax , so recently lung ultrasonography (LUS) incorporated in evaluation and diagnosis of VAP in a new score called sono pulmonary infection score (SPIS) . The (SPIS), where is incorporated LUS finding instead of CXR finding of CPIS is assigned two points for ≥ one area of dynamic air bronchogram. One point was given for ≥ two sub-pleural consolidation or lobar consolidation areas or ≥ one sub-pleural, and ≥one lobar consolidationRecently (combination of SPIS with APACHE score in assessment of VAP is under research ).

研究设计

研究类型
Observational
观察模型
Other
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age >18 yrs
  • Mechanically ventilated patients after first 48 hours of admission in RICU

排除标准

  • Age <18 yrs
  • Patients already diagnosed pneumonia
  • patient refused participation in the study.

结局指标

主要结局

Compined SONOPULMONARY infection score and APACHE score as a predictor of outcome in RICU patients with ventilator associated pneumonia

时间窗: One year

Compined SONOPULMONARY infection score and APACHE score as a predictor of outcome of respiratory intensive care unit patients with ventilator associated pneumonia

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Lamiaa Hussein Fouda

Doctor

Assiut University

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