NCT00015288已完成1 期
PK0496 Pharmacokinetics of Buprenorphine
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 试验地点
- 1
- 主要终点
- Measurements of buprenorphine and naloxone in plasma
研究概览
简要总结
The purpose of this study is to examine pharmacokinetics and dose proportionality of sublingual tablets containing varying doses of buprenorphine and naloxone.
详细描述
The objective of this study is to examine pharmacokinetics and dose proportionality of sublingual tablets containing varying doses of buprenorphine and naloxone.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 21 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male/Female between the ages of 21 and
- •Within 15% of ideal body weight. No oral pathology that would interfere with the sublingual absorption of the medication. Experienced in the use of opiates but not dependent.
排除标准
- •LFT's exceeding than 3x's normal. History of seizure. Opiate dependent.
结局指标
主要结局
Measurements of buprenorphine and naloxone in plasma
Physiological measures
Subjective symptoms measures
次要结局
未报告次要终点
研究者
研究点 (1)
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