Optimal strategy for Cardiovascular risk assessment in Spondyloarthritis : A comparative analysis between traditional cardiovascular risk score (QRISK3 score) versus traditional risk score supplemented with either Carotid ultrasound or Coronary CT angiography
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- To compare the accuracy of Cardiovascular (CV) risk estimation in SpA patients by traditional CV risk prediction tool (QRISK3) alone versus traditional CV risk score (QRISK3) combined with either carotid US or coronary CT angiography
研究概览
简要总结
Inflammatory rheumatic diseases are traditionally considered a risk factor for cardiovascular diseases. However, EULAR has advocated the multiplication of cardiovascular risk-score estimated by traditional cardiovascular risk-scoring tools in patients of rheumatoid arthritis patients by a certain factor. There is no such advice for patients with spondyloarthritis. Besides, all the previous studies failed to identify any higher cardiovascular risk in patients with spondyloarthritis. There is a possibility that the traditional cardiovascular risk score may underestimate the actual cardiovascular risk in patients with spondyloarthritis. This current study is planned to see whether the traditional cardiovascular risk score used for the general population truly underestimates the cardiovascular risk in patients of spondyloarthritis and whether other strategies like carotid ultrasound and CT angiography fare better for cardiovascular risk assessment amongst the patients of spondyloarthritis.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Newly diagnosed case/previously diagnosed case of axial Spondyloarthritis, Ankylosing Spondylitis, or Psoriatic Arthritis.
排除标准
- •Pregnant women and lactating mother
- •History any cardiovascular or cerebrovascular events
- •History of any allergy to contrast agents
- •Presence of chronic kidney disease which is a contraindication for contrast use during CT scan
- •Any other contraindications for radiological investigations like CT or Ultrasound.
结局指标
主要结局
To compare the accuracy of Cardiovascular (CV) risk estimation in SpA patients by traditional CV risk prediction tool (QRISK3) alone versus traditional CV risk score (QRISK3) combined with either carotid US or coronary CT angiography
时间窗: End of study period
次要结局
- To compare the cardiovascular (CV) risk estimation by QRISK3 combined with carotid US versus QRISK3 combined with coronary CT angiography in SpA patients for finding out the best tool for CV risk screening.(End of study period)
研究者
Dr Joydeep Samanta
All India Institute of Medical Sciences (AIIMS), Raipur