MISSION COPD - Modern Innovative SolutionS in Improving Outcomes iN - COPD - A Comparison of Clinical Outcomes Before and After the MISSION Clinic.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 114
- 试验地点
- 1
- 主要终点
- COPD control measured by number of exacerbations treated with steroids and or antibiotics for ≥3 days
研究概览
简要总结
MISSION is a new and novel way of delivering highly specialised Chronic Obstructive Pulmonary Disease (COPD) care and has the potential to change the way COPD care across the UK is delivered as well as services for other long term health conditions. The MISSION model has been piloted in asthma which is the subject of an ongoing research study. This is the first model of this type in COPD and the current research study aims to evaluate the outcomes of the project. This will be done in several different ways. The study is a mixed methods evaluation of the new service comparing outcomes before and after the clinic using retrospective data analysis and prospective qualitative interview. The study will be conducted at Portsmouth Hospitals NHS Trust and will recruit patients who attend MISSION COPD clinics as well as staff who attended MISSION clinics in a professional capacity.
详细描述
The purpose of the study is to evaluate in detail the clinical and health economic outcomes from the MISSION COPD project. MISSION COPD is a quality improvement project funded by the Health Foundation, Foundation with additional funding from Pfizer, to trial an innovative way of finding and assessing patients with COPD and also case finding new diagnoses of COPD.
MISSION-COPD will allow swift early specialist multi-disciplinary interventions in primary care to diagnose and treat those at greatest risk, consistent with the NHS England '5-year Forward View' calling for removal of traditional primary and secondary care barriers. MISSION COPD will target COPD patients with risk factors for exacerbations and deteriorating lung function as well potential new diagnoses of COPD.
The aim of the study is to review the MISSION clinic model outcomes as well as performing qualitative interviews with patients who attended and staff who took part in the project.
Up to 150 patients who attend the MISSION COPD clinic will be recruited along with approximately 20 health care professionals. The number of patients has been decided as the number that can be seen for the project in the MISSION COPD project time and budget.
Participants will be either:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
COPD control measured by number of exacerbations treated with steroids and or antibiotics for ≥3 days
时间窗: 6 months
To assess whether the number COPD exacerbations (prednisolone or equivalent ≥30 mg for \>3 days or antibiotics for \>3 days) improves in MISSION patients in the 6 months after the clinic compared with the 6 months before.
Number of exacerbations of COPD that require hospital admission and treatment
时间窗: 6 months
Number of exacerbations of COPD that require admission to hospital for treatment to assess whether hospital admissions change in the 6 months after the MISSION clinic
次要结局
- St George's Respiratory Questionnaire (SGRQ)(6 months)
- Assessment of eosinophilic airways inflammation(Baseline)
- Frequency and severity of co-morbidities(Baseline)
- Medication adherence(6 months)
- Gastroesophageal Reflux Disease Questionnaire (GERDQ) score(6 months)
- Number of hospital admissions for COPD(6 months)
- COPD Assessment Test (CAT) Score(6 months)
- Number of non elective GP visits for COPD(6 months)
- Number of Emergency Department contacts for COPD(6 months)
- Number of out of hour (OOH) attendances/contacts for COPD(6 months)
- Short acting bronchodilator (SABA) use(6 months)
- Assessment of inhaler technique and recommendations for inhaler devices.(Baseline)
- Smoking cessation advice(Baseline)
- COPD controller medication(6 months)
- Number of antibiotic courses without prednisolone for lower respiratory tract infections(6 months)
- Investigations performed(Baseline)
- Hospital Anxiety and Depression Scale (HADS) score(6 months)
- Global initiative in chronic Obstructive Lung Disease (GOLD) score(Baseline)
- Measurement and variation of lung function.(Baseline)
- Patient activation measure(6 months)
- The frequency of non-attendance at clinic(Baseline)