ISRCTN39138989已完成不适用
The British Thoracic Society trial to assess the safety and efficacy of intra-pleural streptokinase in pleural infectio
Medical Research Council (MRC) (UK)0 个研究点目标入组 500 人开始时间: 2000年10月25日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 500
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Purulent or positive Gram stain or positive culture pleural fluid
- •2. Acidic pleural effusion (pH less than 7.2) in the presence of clinical pneumonia
排除标准
- •1. Age less than 18 years
- •2. A serious illness making survival at three months unlikely.
- •3. Previous intrapleural fibrinolytics for this empyema
- •4. Previous video assisted thoracoscopic drainage, thoracotomy, pleural decortification or open drainage for this empyema
- •5. Known sensitivity to streptokinase.
- •6. Coincidental stroke or major haemorrhage
- •7. Major surgery within previous 5 days
- •8. Previous pneumonectomy on same side of infection.
- •9. Pleural malignancy
- •10. females who are pregnant or lactating
研究者
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