Efficacy of tranexamic acid in reducing bleeding in patients undergoing total knee arthroplasty

Fundacao Hospital Adriano Jorge0 个研究点开始时间: 2019年10月16日最近更新: 2023年5月29日

适应症

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•Patients were regularly enrolled in the institution where the study was performed with a classic indication of TKA, recommended by Camanho: medial or lateral clamping with obliteration of the joint space, deviations in femoro-tibial varus greater than 15º; deviations in femoro-tibial valgus greater than 10º; femorotibial subluxation in the frontal plane greater than 10 mm; anteriorization of the tibia in relation to the femur in the profile radiography; severe involvement of two of the three knee joint compartments (femorotibial medial, femorotibial lateral or femoropatellar), and failure of conservative treatment for at least three months, when these criteria were not fulfilled. Patients with primary degenerative knee OA; for this evaluation, the patients with stage of knee arthrosis III were considered, according to Ählback, modified by Keys

•Patients who underwent knee prosthesis revision surgery, who did not use medial articular access, patients not operated by the senior surgeon, patients with rheumatoid arthritis, multiple scars, and those who refused to sign or did not understand were excluded from the study. TCLE. Any patient with decompensated diabetes mellitus (fasting glycemia> 140 mg / dL), uncontrolled systemic hypertension (SBP > 200 mmHg), peripheral vascular disease, previous thromboembolic events, acute myocardial infarction, neoplasia, active infection, rheumatoid arthritis, obese with (American Society of Anesthesiologists - ASA score> III) and use of anticoagulants had their clinical condition reassessed and surgical procedure postponed. Patients who declared themselves indigenous

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