2023-505726-34-02尚未招募4 期
Studies to gain insight how the drugs PCSK9-inhibitors and statins affect cholesterol and bile acid metabolism
Karolinska University Hospital1 个研究点 分布在 1 个国家目标入组 8 人开始时间: 2024年4月12日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 8
- 试验地点
- 1
- 主要终点
- Changes in the measured parameters of cholesterol and bile acid metabolism
研究概览
简要总结
To learn more about the effects of the drugs statin (atorvastatin) and PCSK9 inhibitors (evolocumab) on the metabolism of cholesterol and bile acids in the human body.
入排标准
- 年龄范围
- 18 years 至 64 years（18-64 Years）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •18-64 year old
排除标准
- •Cardiovascular disease
- •Any chronic medication use
- •Steroid treatment for the last six months or HRT
- •Coagulopathy
- •Musculoskeletal or neurologic disease
- •Inclusion in any other concurrent medical research study
- •Cerebrovascular disease (e.g. stroke, prior aneurysm)
- •Pulmonary disease (e.g. pulmonary hypertension, COPD)
- •Metabolic disease (incl. but not limited to Cushing disease, Diabetes)
- •Renal disease (by CKD criteria)
- •Active inflammatory bowel syndrome
结局指标
主要结局
Changes in the measured parameters of cholesterol and bile acid metabolism
Changes in the measured parameters of cholesterol and bile acid metabolism
次要结局
未报告次要终点
研究者
Mats Eriksson
Scientific
Karolinska University Hospital
研究点 (1)
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