The STop UNhealthy Substance Use Now Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 144
- 试验地点
- 6
- 主要终点
- Number of adults screened for substance use disorder
研究概览
简要总结
The STop UNhealthy (STUN) Substance Use Now Trial (STUN II) is a multisite trial aiming to evaluate the comparative effectiveness of the following strategies for improving the implementation of screening and interventions for substance use disorders in primary care: practice facilitation (PF), PF plus a learning collaborative (LC), PF plus performance incentives (PI), and PF+LC+PI. We plan to enroll 144 clinic staff participants from 48 primary care practices
详细描述
The STop UNhealthy (STUN) Substance Use Now Trial (STUN II) is a multisite trial aiming to evaluate the comparative effectiveness of the following strategies for improving the implementation of screening and interventions for substance use disorders in primary care: practice facilitation (PF), PF plus a learning collaborative (LC), PF plus performance incentives (PI), and PF+LC+PI. We plan to enroll 144 clinic staff participants from 48 primary care practices
Specific aim 1 (primary aim) will compare the effect of learning collaborative (LC) participation, performance incentives (PI), or their combination, with practice facilitation (PF) only, on implementation of evidence-based screening for SUDs.
Specific aim 2 (secondary aim) will compare the effect of LC participation, PI, or their combination, with PF only, on implementation of evidence-based interventions for SUDs, including (a) brief counseling, (b) medications (e.g., buprenorphine, naltrexone) and adherence to them, and (c) referral to specialty care.
Specific aims 1 and 2 will produce fundamentally important evidence about the comparative effectiveness of PF, PF+LC, PF+PI, and PF+LC+PI strategies on uptake of evidence-based screening and interventions for SUD when delivered to primary care practices.
Specific aim 3 (exploratory aim) will use a longitudinal mixed-methods evaluation to assess the association between implementation effectiveness and putative moderators (e.g., organizational readiness for change) and mediators (e.g., implementation climate). Aim 3 will generate scientific knowledge about mechanisms of change (why and how the various strategies work) in primary care settings.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Clinic staff members from primary care practices who provide care for adult patients and have a leadership role within the practice (e.g. lead physician, practice manager, lead medical assistant/nurse, clinical champion)
排除标准
- •Clinic staff members who already have ongoing involvement in programs that would conflict with or preclude this study
结局指标
主要结局
Number of adults screened for substance use disorder
时间窗: 12 months
Number of people aged 18 and older who are screened for substance use disorder using a validated screening tool
Percent of adults screened for substance use disorder
时间窗: 12 months
Percent of people aged 18 and older who are screened for substance use disorder using a validated screening tool
次要结局
- Percentage of adults who received medication for substance use disorder, including alcohol use disorder(12 months)
- Number of adults who received medication for substance use disorder, including alcohol use disorder, and adhered to 6 months of treatment(24 months)
- Percentage of adults who received medication for substance use disorder, including alcohol use disorder, and adhered to 6 months of treatment(12 months)
- Percent of adults with a positive screen for substance use disorder(24 months)
- Number of adults with a positive screen for substance use disorder(24 months)
- Percentage of adults who received medication for substance use disorder(24 months)
- Number of adults who received any evidence-based intervention for alcohol use disorder(24 months)
- Number of adults who received medication for alcohol use disorder(24 months)
- Percentage of adults who received medication for alcohol use disorder(12 months)
- Percentage of adults who received medication for alcohol use disorder and adhered to 6 months of treatment(12 months)
- Number of adults referred to specialty care for alcohol use disorder(24 months)
- Number of adults screened for substance use disorder(24 months)
- Percent of adults screened for substance use disorder(24 months)
- Number of adults who received any evidence-based intervention for substance use disorder(24 months)
- Number of adults who received medication for substance use disorder(24 months)
- Number of adults who received medication for alcohol use disorder and adhered to 6 months of treatment(24 months)
- Percentage of adults who received any evidence-based intervention for substance use disorder(12 months)
- Number of adults who received brief counseling for substance use disorder(24 months)
- Percentage of adults who received brief counseling for substance use disorder(12 months)
- Number of adults referred to specialty care for substance use disorder and/or alcohol use disorder(24 months)
- Percentage of adults referred to specialty care for substance use disorder and/or alcohol use disorder(12 months)
- Number of adults with alcohol use disorder(24 months)
- Percentage of adults with alcohol use disorder(12 months)
- Percentage of adults who received any evidence-based intervention for alcohol use disorder(12 months)
- Percentage of adults referred to specialty care for alcohol use disorder(12 months)
- Number of adults who received brief counseling for alcohol use disorder(24 months)
- Percentage of adults who received brief counseling for alcohol use disorder(12 months)
研究者
Dan.Jonas
Director and Professor, Division of General Internal Medicine
Ohio State University