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临床试验/NCT00194220
NCT00194220已完成不适用

Markers in Women Undergoing Infertility Treatment

University of Pennsylvania1 个研究点 分布在 1 个国家目标入组 1,235 人开始时间: 2002年9月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
1,235
试验地点
1

研究概览

简要总结

This study is only collecting specimens from current patients of PENN Fertility Care.

The purpose of this investigation is to assess if markers of oxidative stress that are known to be associated with other medical conditions can be detected in women undergoing infertility treatment and normal women of similar age. Oxidative stress may affect a woman's eggs or the follicular cells that surround and nurture them. Other markers of to be investigated include markers of cellular aging and DNA structural changes.

Presence of these markers will be compared in blood and urine samples taken during infertility treatment, and follicular fluid at the time of IVF (if applicable).

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 50 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Women aged 18-50
  • Infertility patients only:
  • Women undergoing infertility treatment (with or without in-vitro fertilization) at the University of Pennsylvania's PENN Fertility Care
  • Verified infertility diagnosis of any of the following:
  • Endometriosis (minimal or mild)
  • Endometriosis (moderate or severe)
  • Tubal factor
  • Hypogonadotrophic hypogonadism
  • Polycystic ovary syndrome
  • Diminished ovarian reserve
  • Male factor
  • Unexplained
  • Healthy normal volunteers only:
  • Not undergoing infertility treatment
  • Not using hormonal contraception

排除标准

  • Currently pregnant or breastfeeding
  • Post-menopausal
  • Concurrent participation in investigational trial
  • Other health problems which, in the opinion of the investigator, may affect participation

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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