跳至主要内容
临床试验/NCT06484127
NCT06484127已完成不适用

Heterogeneity of Tertiary Lymphoid Structures Predicts Distinct Malignancy and Immune Microenvironment in Prostate Cancer: a Retrospective Cohort Study

Fudan University1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2023年12月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
200
试验地点
1
主要终点
Correlation between the detection of TLS(tertiary lymphoid structure) and clinical features

研究概览

简要总结

The aim of this study was to reveal the predictive value of spatial heterogeneity and maturity difference of tertiary lymphoid structure in pathological sections of prostate cancer patients for clinical features and prognosis. It provides a new idea for the selection of prostate cancer immunotherapy population in the future.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

性别
Male
接受健康志愿者

入选标准

  • 1.patients diagnosed with prostate cancer who underwent radical prostatectomy or prostate puncture

排除标准

  • incomplete medical records, inadequate follow-up information, and confirmed non-prostatic acinar adenocarcinoma.

结局指标

主要结局

Correlation between the detection of TLS(tertiary lymphoid structure) and clinical features

时间窗: 1 month

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Wang Zhongyuan

Study Director

Fudan University

研究点 (1)

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