Bathing Additives in Management of Pediatric Atopic Dermatitis
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- Mayo Clinic
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- EASI score at 6 months
研究概览
简要总结
The current clinical guidelines for management of atopic dermatitis now recommend bleach baths. This requires simply the addition of regular household bleach to twice-weekly baths. At the Mayo Clinic, dilute acetic acid (vinegar) has been recommended for decades in wet wraps to treat patients hospitalized for their atopic dermatitis. However, this practice has not been widely adopted in the pediatric dermatology community. Will the use of dilute acetic acid (vinegar) in twice weekly baths help manage atopic dermatitis in pediatric patients as well as, or better than, the current accepted guidelines?
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 6 Months 至 17 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients from 6 months to 17 years of age
- •Currently residing in US.
- •Follow up visits at 1 month, 3 months and 6 months after initiation of treatment in study (Figure 1).
- •Last follow-up at 1 year in clinic or via written mailed-out survey.
- •Diagnosis of atopic dermatitis AND
- •Have active signs of bacterial skin infection OR
- •Any documented suspected history of bacterial skin infection (weeping, crusting, and/or pustules on exam), OR
- •Prescription for oral antibiotics for skin infection in the past 6 months from any provider). OR
- •Have been prescribed bleach baths as part of an atopic dermatitis skin care regimen.
排除标准
- •Superficial skin infection without diagnosis of atopic dermatitis
- •Lack of in-clinic follow up assessment at 6 months
研究组 & 干预措施
Bleach
Patients will use bleach added to their baths twice a week.
干预措施: Bathing Additive (Other)
Vinegar
Patients will use vinegar (dilute acetic acid) added to their baths twice a week.
干预措施: Bathing Additive (Other)
结局指标
主要结局
EASI score at 6 months
时间窗: 6 months
次要结局
- Courses of antibiotics required(1 year)