Retrospective Study of the Protective Effect of Gastrodin on Myocardium in Patients Undergoing Cardiac Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 160
- 试验地点
- 1
- 主要终点
- The degree of myocardial injury
研究概览
简要总结
Retrospective collection of Wuhan Union hospital from December 1,2018 to June 30,2021 to meet the entry and discharge standards. The patient 's medical record data were divided into study group and control group according to the use of gastrodin during operation. The perioperative data and prognostic outcomes in the patient 's medical records were collected and analyzed. The degree of myocardial injury and postoperative clinical outcomes were compared between the two groups.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged≥18 years, regardless of gender;
- •Patients undergoing elective cardiac surgery under general anesthesia;
- •ASA grade 1 ~ 3.
排除标准
- •Suffering from more serious genetic diseases (such as immunodeficiency, thalassemia, etc.);
- •Moderate to severe malnutrition, moderate to severe anemia;
- •Persistent infection;
- •Severe preoperative underlying diseases (such as severe liver and kidney dysfunction)
结局指标
主要结局
The degree of myocardial injury
时间窗: The myocardial tissue was collected during the operation. About 2 hours on average
The myocardial tissue trimmed by the surgeon according to the surgical requirements was collected during the operation for electron microscopy observation and detection of related molecular content.
次要结局
未报告次要终点