ISRCTN56435384进行中（未招募）Unknown
The effects of de-epithelialization on palatal gingival graft healing
适应症
试验速览
- 阶段
- Unknown
- 状态
- 进行中（未招募）
- 入组人数
- 25
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Aged between 21-38 years old
- •2. No systemic diseases; no coagulation disorders; no medications affecting wound healing or periodontal tissues in the previous 6 months; no pregnancy or lactation; no allergy or other contraindication to study medications
- •3. No tobacco or marijuana use; exhaled air carbon monoxide <8 ppm
- •4. Absence of untreated caries lesions, extensive caries history, untreated periodontitis, history of cleft palate, inadequate endodontic therapy or tooth mobility >1 on maxillary teeth; full-mouth plaque score [FMPS] and full-mouth bleeding score [FMBS] = 20% at study entry
- •5. No previous periodontal surgery on the palatal masticatory mucosa (donor area)
- •6. Adequate apico-coronal space (palatal vault height and upper arch shape) and mouth opening for required wound size and instrument use
- •7. Ability to tolerate maxillary impression making and use of palatal template, i.e., lack of strong gag reflex
- •8. No contraindication to receiving any study medications (anesthetics and analgesics), or gingival surgery
排除标准
- •1. Tobacco or marijuana user, or have used any tobacco products in the last 2 years
- •2. Unable or unwilling to refrain from drinking alcohol during the two weeks of the study
- •3. Unable or unwilling to refrain from consuming caffeine (in any form) for 3 hours before any of the study visits
- •4. Unable or unwilling to refrain from exercising for 3 hours before any of the study visits
- •5. Diagnosed with an uncontrolled systemic disease, such as high blood pressure (hypertension), seizures (epilepsy), high blood sugar (diabetes)
- •6. Disease or medication that affects blood clotting
- •7. History of systemic disease affecting healing, such as diabetes
- •9. Taking medications that can affect the gum tissues
- •10. Taking medications that can affect wound healing
- •11. Pregnant, or lactating, or using contraceptive medications
- •12. Allergic to any of the materials (impression materials, acrylic plastic) or medications (topical or local dental anesthetic; analgesic medication; cyanoacrylate) used in the study
- •13. Untreated periodontitis (gum) disease
- •14. Upper (maxillary) teeth that are loose (mobile), or have untreated cavities (caries), or poor or questionable root canal treatment
- •15. Inadequate oral hygiene or inflamed or swollen gums
- •16. History of surgery on the roof of the mouth
- •17. Conditions or diseases affecting the roof of your mouth
- •18. Use of any removable oral appliances for the upper jaw
- •19. Gag easily
- •20. The shape (steepness) of the roof of the mouth could prevent study procedures
- •21. Contraindication to receiving study medications or procedures
- •22. Unable or unwilling to adhere to the study visit schedule
- •23. Unable or unwilling to provide written informed consent
研究者
相似试验
招募中
不适用
The influence of cheek fat removal on face measurements, satisfaction with facial esthetics and quality of life: a clinical trialRBR-6dzcg8gCentro Universitário Christus - UNICHRISTUS
已完成
不适用
Influence Of Modification Of Palatal Contour Of Upper Denture On SpeechCTRI/2020/12/029993Dr prerna priyadarshni
Unknown
不适用
Tuberosity Versus Palatal Donor Site for Subepithelial Connective Tissue Graft in Root Coverage Therapy (TOPGRAFT)Gingival RecessionNCT03661619Assistance Publique - Hôpitaux de Paris38
尚未招募
不适用
Role of tonsilar epithelium in oral toleranceAllergienT78.4Allergy, unspecifiedDRKS00005424Zentrum für Kinder- und Jugendmedizin der Universitätsklinik Freiburg, Arbeitsgruppe Allergologie, Pulmologie und Cystische Fibrose40
尚未招募
Unknown
Presence of gingival exhibit in smile lines of various age groups and gender.CTRI/2023/06/053423one