NCT02009371已完成不适用
A Clinical Study of Light Therapy on Depressive Episodes of Bipolar Disorder
Peking University1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2013年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Reducing rate of HAMD
研究概览
简要总结
The purpose of this study is to investigate the efficacy and safety of light-emitting diode(LED) light therapy on Chinese patients with Depressive Episodes of Bipolar Disorder and to gather prime research data and application parameters of LED light source which is not currently available in China.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ages 18 to 65 years
- •comply with the DSM-IV diagnosis of Bipolar I or II Disorder and a current depressive episode
- •HAMD score ≥17 points
- •intake of just one particular psychotropic drug(a mood stabilizer or an atypical antipsychotic drug) except of antidepressants and lasted 2 weeks.
排除标准
- •inability to provide informed consent;
- •previous treatment with BLT
- •presence of another major psychiatric illness such as schizophrenia, schizoaffective disorder, lifetime alcohol or substance dependence
- •diagnosed with a rapid-cycling bipolar disorder or currently in the mixed state or YMRS score>12 points
- •use of antidepressants medications
- •significant medical illness such as diabetes mellitus,heart failure, renal failure, severe liver function abnormalities,hyperthyroidism or hypothyroidism
- •pregnancy;
- •received magnified electroconvulsive therapy orRepetitive Transcranial Magnetic Stimulation in the past 3 months
- •an eye condition that could be negatively affected by bright light
- •suicidal risk or other factor making trial participation clinically inappropriate.
结局指标
主要结局
Reducing rate of HAMD
时间窗: Change from baselin to 2 weeks after
We used HAMD to evaluate the major state of depression.
次要结局
- Reducing rate of CGI(Change from baseline to 2 week after)
研究者
Xin Yu
President
Peking University
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Transcranial Laser Therapy for Major Depressive DisorderMajor Depressive DisorderNCT01538199Paolo Cassano28
终止
不适用
Bright Light Therapy for Depression Symptoms in Adults With Cystic Fibrosis (CF) and COPDDepressive SymptomsCystic FibrosisChronic Obstructive Pulmonary DiseaseNCT04921332Erica Osborn4
已完成
不适用
Bright Light Therapy as Augmentation of Depressive Symptoms on Acute Psychiatric FloorDepressionNCT04385394State University of New York - Upstate Medical University100
已完成
不适用
The effects of bright light therapy for depression in adults with intellectual disability.DepressionNL-OMON44100Erasmus MC, Universitair Medisch Centrum Rotterdam171
尚未招募
不适用
The effect of light therapy on depression in adults with intellectual disabilities.The primary outcome is depressive symptoms. Depressive symptoms will be primarily studied, because diagnosing a major depressive disorder is not always possible in people with intellectual disabilities due to diagnostic difficulties related to their limited cognitive abilities.Secondary outcome measures are major depression, circadian rhythm and stress.NL-OMON24095Erasmus MC, University Medical Center RotterdamIpse de Bruggen, ZwammerdamAmarant Groep, TilburgAbrona, Huis ter Heide219