Pharmacological Risk Modification for Progression into Symptomatic Dementia: Complete Enumeration Study Utilizing Administrative Claims Record in Kashiwa City - Pharmacological Risk Modification for Progression into Symptomatic Dementia

In addition to older age and female sex, use of the following medications was significantly associated with NPADM: statins (HR: 0.82; p=0.001), antihypertensives (HR: 0.80; p<0.0001), non-steroidal bronchodilators (HR: 0.728; p=0.002), antidepressants (HR: 1.79; p<0.0001), poststroke medications (HR: 1.45; p=0.002), insulin (HR: 1.34; p=0.046) and antineoplastics (HR: 1.12; p=0.035).