An Open Label Randomized Comparative Clinical Study To Evaluate The Efficacy Of Amalaki Rasayana And Triphala Rasayana In Seminal Hyperviscosity Vis-À-Vis Kaphaja Shukra Dushti
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
研究概览
简要总结
This study is an open label randomized comparative clinical trial conducted to evaluate the efficacy of Amalaki Rasayana and Triphala Rasayana in the management of seminal hyperviscosity, which is correlated with Kaphaja Shukra Dushti in Ayurveda. Male infertility contributes significantly to reproductive challenges, and seminal hyperviscosity is an important factor affecting sperm motility and fertility. In Ayurvedic classics, Kaphaja Shukra Dushti is characterized by excessive picchilata, which can be correlated with increased semen viscosity and delayed liquefaction time.
The study aims to assess the individual effects of Amalaki Rasayana and Triphala Rasayana on picchilata and to compare their therapeutic efficacy. A total of 40 male subjects aged 25 to 45 years fulfilling the inclusion criteria will be selected and randomly divided into two groups of 20 each. Group A will receive Amalaki Rasayana and Group B will receive Triphala Rasayana in a dose of 12 grams twice daily with milk after food for 30 days.
Assessment will be based on objective semen analysis parameters as per WHO 2021 guidelines, specifically liquefaction time greater than 60 minutes and semen viscosity more than 2 cm thread formation. Statistical analysis will be done using paired and unpaired t tests. Ethical clearance has been obtained and the study is conducted on human subjects only.
The research intends to provide clinical evidence for the role of Rasayana therapy in improving seminal parameters and managing Kaphaja Shukra Dushti associated with male infertility.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 25.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- Male
入选标准
- •Subjects with symptoms of Kaphaja Shukra Dushti (Atipcchilata /hyper seminal viscosity).
- •Subjects willing to sign and give consent.
- •known case of primary and secondary infertility.
排除标准
- •Known case of HTN and DM. 2) Diagnosed case of Varicocele (moderate to severe) and Cryptorchidism. 3) Known case of STD and Retroviral Diseases and TB. 4) Congenital obstructions of seminal ducts. 5) Diagnosed subjects of Chronic illness.
- •Chronic Kidney Disease. 6) Known case of Genetic disorder.
- •Youngs Syndrome and Klinefelter Syndrome and Kartageners syndrome and Celiac disease. 7) Diagnosed subjects of Cancer and ongoing chemotherapy.
研究者
DR CHAVAN PRASHANT DILIP
JSS Ayurveda Medical College