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临床试验/NCT01153594
NCT01153594已完成3 期

Early Re-Intervention (ERI) Experiment 2

Chestnut Health Systems2 个研究点 分布在 1 个国家目标入组 446 人开始时间: 2004年2月最近更新:
适应症

试验速览

阶段
3 期
状态
已完成
入组人数
446
试验地点
2
主要终点
Time to First Alcohol or Drug Treatment Re-Entry

研究概览

简要总结

The objective of this study was to evaluate the relative effectiveness of quarterly Recovery Management Checkups (RMC) on long-term outcomes of adult chronic substance users over 4 years.

详细描述

CONTEXT: While drug abuse is the 10th leading cause of mortality in the US, the disorder remains an orphan of the public health care system. Unlike cancer, diabetes, and other chronic diseases, the detection, re-emergence, and progression of which we have learned to respond with aggressively timed monitoring and interventions, drug abuse remains isolated from adoption into the "chronic condition" model of care.

OBJECTIVES AND HYPOTHESES: The objective of this study was to evaluate the relative effectiveness of quarterly checkups on long-term outcomes of adult chronic substance users over 4 years. Relative to participants randomly assigned to the control group, we predicted that RMC participants would: H1) return to treatment sooner, H2) receive more treatment, H3) decrease substance use, and H4) increase days of abstinence.

METHOD: Participants were recruited from sequential intakes at the largest addiction treatment agency in Illinois between February and April of 2004. Inclusion criteria were: any substance use in the past 90 days and any past-year symptoms of substance use disorders. For logistical reasons, participants were excluded if they were: under 18, lived or planned to move outside Chicago within 12 months, sentenced to a confined environment most of the next 12 months, mandated to treatment because of a driving under the influence offense, were not fluent in English or Spanish, or were cognitively unable to provide informed consent. To evaluate efficacy of quarterly Recovery Management Checkups (RMC) on treatment reentry and substance use, 446 adults (88% with dependence criteria) were randomly assigned quarterly RMCs, or, an outcome monitoring only control group and followed quarterly for 4 years (94% completion).

INTERVENTION. After interviewers completed the quarterly research interview and determined participants' eligibility and need for early re-intervention, they transferred RMC participants who were eligible and in need to a Linkage Manager. Using motivational interviewing, the Linkage Manager: a) provided feedback to participants regarding their current substance use and related problems, b) discussed implications of managing addiction as a chronic condition, c) discussed treatment barriers and solutions, d) assessed and discussed level of motivation for treatment, e) scheduled treatment appointments, f) accompanied participants to treatment intake and stayed through the process, and g) implemented Engagement and Retention Protocol during the 14 days of treatment. Detailed procedures and forms are available in the RMC manual(Scott & Dennis, 2003; http://www.chestnut.org/LI/downloads/Scott_\&_Dennis_2003_RMC_Manual-2_25_03.pdf ).

OUTCOME MEASURES: Days to first treatment, days of treatment, successive quarters of needing treatment, number of substance problem months, days of abstinence.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • any substance use in the past 90 days
  • any past-year symptoms of substance use disorders.

排除标准

  • lived or planned to move outside Chicago within 12 months
  • sentenced to a confined environment most of the next 12 months
  • mandated to treatment because of a driving under the influence offense
  • were not fluent in English or Spanish
  • were cognitively unable to provide informed consent.

结局指标

主要结局

Time to First Alcohol or Drug Treatment Re-Entry

时间窗: Quarterly from random assignment until month 48

Days to readmission was calculated as the number of days from the date of the quarterly follow-up interview where the client first reported being in need of treatment (see below) to the date of the first subsequent intake to alcohol or other drug treatment following that interview.

次要结局

  • Any Treatment Re-Entry(Quarterly from random assignment until month 48)
  • Times Re-entered Treatment Time Frame(Quarterly from random assignment until month 48 Description:)
  • Total Days of Treatment(Quarterly from random assignment until month 48)
  • Quarters with 7 days Outpatient or 14 days Residential(Quarterly from random assignment until month 48)
  • Quarters Needing Treatment(Quarterly from random assignment until month 48)
  • Successive Quarters Needing Treatment(Quarterly from random assignment until month 48)
  • Substance Problem x Months(Quarterly from random assignment until month 48)
  • Total Days of Abstinence(Quarterly from random assignment until month 48)

研究者

申办方类型
Other

研究点 (2)

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