Development of Non-invasive Method for Quantifying Vitamin D Levels in the Body Using Spectroscopy
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Vitamin D levels
研究概览
简要总结
Lack in vitamin D reduces the absorption of calcium in the body, accelerates bone loss and may increase the risk of fractures due to osteoporosis. An algorithm that will allow immediate and non-invasive quantification of vitamin D levels will shorten the time of diagnosis, reduce lab costs and prevent hazards or discomfort to the patient associated with a blood test.
The goal of the study is therefore to develop a non-invasive method for quantifying vitamin D levels in the body using spectroscopy.
40 subjects will be recruited: 20 hospitalized patients in the rehabilitation department, diagnosed with osteoporosis and 20 healthy subjects. Spectroscopy will be used with visible light on the subject's skin and middle infrared (MIR) on the blood sample to find correlation with the chemical lab test results.
详细描述
Lack in vitamin D reduces the absorption of calcium in the body, accelerates bone loss and may increase the risk of fractures due to osteoporosis. Vitamin D can be ingested by foods and specific supplements, but the main source for the vitamin is its synthesis in the skin by using sun radiation. Today, quantification of vitamin D levels is performed using a blood test. Mostly, the physician will send the patient to check the levels and vitamin D if he suffers from osteoporosis, hypertension, renal impairment, suspected for activity of the thyroid gland, tuberculosis or sarcoidosis.
Studies have shown that it is possible to quantify the different elements in the contents of the blood, such as melanin and hemoglobin, using spectroscopy of the skin (Zonios et al, 2001; Tseng et al, 2009), but to the investigators' knowledge, the identification of levels and vitamin D in similar means has not been reported in professional literature.
The rationale for this research: an algorithm that will allow immediate and non-invasive quantification of vitamin D levels will shorten the time of diagnosis, reduce lab costs and prevent hazards or discomfort to the patient associated with a blood test.
The goal of this study is therefore to develop a non-invasive method for quantifying vitamin D levels in the body using spectroscopy.
Methods:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •Cannot understand or sign a consent form independently
结局指标
主要结局
Vitamin D levels
时间窗: At baseline
No followup will be performed.
次要结局
未报告次要终点