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临床试验/NCT05793697
NCT05793697尚未招募不适用

Assessment Of Different Scores In Predicting Outcome In Acute Exacerbation Of Chronic Obstructive Pulmonary Disease Patients In Emergency Department

Assiut University0 个研究点目标入组 139 人开始时间: 2023年5月3日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
139
主要终点
Evaluate the value of different scores in predicting hospital mortality

研究概览

简要总结

evaluate the value of different scores in predicting hospital mortality and Need for MV In patients presented to ED with AECOPD.

详细描述

Chronic obstructive pulmonary disease (COPD) is one of the top three causes of death worldwide, and 90% of deaths occur in low- and middle-income countries.

Acute exacerbation of chronic obstructive pulmonary disease(AECOPD) is defined as an acute change in patient's dyspnea, cough, or sputum beyond normal variability that is sufficient to warrant a change in therapy. AECOPD has a negative effect on the quality of life, admission and readmission rates, and disease progression.

For these reasons, appropriate management of acute exacerbations is recommended by national and international organizations.

Identifying high-risk dying patients on hospital admission helps in triaging them to the required level of care.

The use of early warning scores in follow-up is recommended for the early detection of critically ill patients and the prediction of clinical deterioration. CURB65, BAP65, qSOFA , DECAF and NEWS, which mainly involve mental status, respiratory rate, oxygen saturations, pulse, blood pressure, age, BUN level, etc., can be used to predict AECOPD-associated mortality in ED given the simple structure and data availability.

研究设计

研究类型
Observational
观察模型
Case Crossover
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All patient presented to ED with acute exacerbation of COPD.

排除标准

  • Patient presented with acute insult affecting other system.
  • Patient transferred to other centers.
  • Inadequate data.

结局指标

主要结局

Evaluate the value of different scores in predicting hospital mortality

时间窗: one year

Assessment Of Different Scores In Predicting Outcome In Acute Exacerbation Of Chronic Obstructive Pulmonary Disease Patients In Emergency Department as DECAF(dyspnea grade V according to eMRCD,esinopenia\<0.05x10\*9/L,consolidation,acidemia\<7.30,atrial fibrillation) 1=mild,2_3=moderate,4_5=severe can be used to predict AECOPD-associated mortality in ED given the simple structure and data availability.

次要结局

  • Value of these scores in predicting need for MV.(one year)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohammed Mostafa Saleh Hussein

Principal investigator

Assiut University

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