Efficacy Of Surgical Plethysmographic Index-guided Analgesia Versus Conventional Analgesia Technique In Laparoscopic Cholecystectomy Using Remifentanil
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 184
- 试验地点
- 1
研究概览
简要总结
Study comparing surgical plethysmographic index guided analgesia with conventional analgesia technique using remifentanil in patients undergoing laparoscopic cholecystectomy. The aim of the study is to evaluate whether intraoperative analgesia guided by surgical plethysmographic index provides better hemodynamic stability and optimized opioid consumption compared to conventional analgesia technique. A total of 184 adult patients will be randomly allocated into two groups. One group will receive analgesia guided by surgical plethysmographic index and the other group will receive conventional analgesia based on standard clinical parameters. Intraoperative hemodynamic variables, total opioid consumption and postoperative pain scores will be assessed and compared between the two groups
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Both males and females, aged 18-65 years ASA physical classification I to II.
排除标准
- •Known uncontrolled cardiovascular disease (e.g., hypertension, systolic and diastolic dysfunction) Liver function abnormality (liver enzymes more than 2 times the normal range) Kidney function abnormality (serum creatinine more than 1.4 mg/dl) Known psychiatric or neurological disorder Known uncontrolled endocrine disorder (diabetes mellitus, hypothyroidism) Known allergy or hypersensitivity to the study drug Recent intake of sedative medication or anti-psychotic medication Substance abuse Anticipated need for postoperative ventilation Refusal to informed consent.
研究者
Dr Naresh Dua
Sir Ganga Ram Hospital