Role of Aloe Vera Versus Fluoride Toothpaste in Changing High to Low Salivary Bacterial Count :Randomized Controlled Trial
试验速览
- 阶段
- 2 期
- 入组人数
- 58
- 试验地点
- 1
- 主要终点
- salivary bacterial count
研究概览
简要总结
Patient's salivary bacterial count will be evaluated , then the patient will bbe instructed to follow oral hygiene measures including the use of aloe vera toothpaste or fluoride toothpaste , the after 15 days and 30 days the patient's salivary bacterial count will be evaluated another time.
详细描述
Variables of study:
Each patient will be instructed to follow oral hygiene measures including aloe vera or fluoride toothpaste
Outcomes:
Salivary bacterial count will be evaluated using Mitis salivarius agar plates before the use of the aloe vera toothpaste then after 15 days then after 30 days .
Participant timeline:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
盲法说明
A participant will generate the random allocation sequence. The researcher will enroll the patients but an unbiased participant will assign the intervention/Control identification procedures .The participants will be blinded to intervention/control assessment methods. Also, it will not be allowed among the examiners to exchange any information throughout the entire study period.
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients should have poor oral hygiene.
- •Patients should have high bacterial count
排除标准
- •Patients with a compromised medical history.
- •Severe or active periodontal disease .
研究组 & 干预措施
aloe vera toothpaste
aloe vera toothpaste isa will be administrated 2 times per day for 30 days and salivary bacterial count will be tested before the use of toothpaste the after 15 days and 30 days
干预措施: aloe vera toothpaste (Drug)
fluoride toothpaste
fluoride toothpaste isa herbal toothpaste will be administrated 2 times per day for 30 days and salivary bacterial count will be tested before the use of toothpaste the after 15 days and 30 days
干预措施: fluoride toothpaste (Drug)
结局指标
主要结局
salivary bacterial count
时间窗: average of 30 days
will be done using mitis salivarius agar plate
次要结局
未报告次要终点
研究者
Neven Ahmed Ebrahim
principal investigator, resident at conservative department
Cairo University