Osteoarticular Sepsis In Intensive Care Units : a Retrospective Study About Deceased Patients.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Epidemiological description of deceased patients
研究概览
简要总结
This is an observational, retrospective, multicenter study based on the use of demographic, clinical and biological data from deceased patients admitted between 2018 and 2022 to critical care with a principal or associated diagnosis of joint prosthesis infection.
Data from this study will be combined with that from the OASIS study (APHP241174/ ID-RCB: 2024-A01769-38) concerning osteoarticular sepsis on prosthetic material in critical care of living patients.
The aim of this study is to improve our knowledge of the profile, care trajectories and outcomes of patients hospitalized in critical care in the context of osteoarticular material sepsis.
The results of the study could help identify at-risk populations and improve management strategies for patients with osteoarticular sepsis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient aged 18 years or older.
- •Hospitalization in critical care (intensive care unit or continuing care unit) between 2018 and 2022, lasting at least 48 hours, with a prosthetic joint infection (hip, knee, or shoulder prosthesis infection) as the primary or associated diagnosis.
- •Deceased patient who had not refused data processing.
排除标准
- •Infection involving osteosynthesis material
- •Infection involving spinal instrumentation
- •Patient with multiple infected prostheses
- •Recurrence of prosthetic infection with the same microorganism as a previous episode
- •Patient under legal protection
- •Pregnant or breastfeeding patient
- •Patient deprived of liberty
结局指标
主要结局
Epidemiological description of deceased patients
时间窗: 2 years
Demographic data, medical history, history of Periprosthetic Joint Infection (timing, diagnosis, surgery, antibiotics), data in intensive care unit (leng of stay, organ failure, drugs and mechanical support, biological data) and outcome (time of death within 2 years after admission to Intensive Care Units).
次要结局
- Mortality at 2 years(2 years)
- Composite endpoint reflecting poor clinical outcome(2 years)
- Epidemiological description based on the number (n) and proportion (%) of bacterial strains found in samples collected during the operation.(2 years)