NCT05690542尚未招募不适用
Nanoparticles in Blood: Understanding and Controlling Protein Corona for Optimized Nanomedicine
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- impact of nanoparticles on coagulation tests ou platelet functions
研究概览
简要总结
The main objective is to study the effect of engineered nanoparticles SPIONs (superparamagnetic iron oxide) on hemostasis. Nanoparticles will be incubated in blood and platelet aggregation will be measured. In parallel, nanoparticles will also be incubated in blood and then plasma proteins adsorbed on them will be separated and analyzed. The proteins found on the nanoparticles will be linked to the platelet aggregation observed to help developing innovative protein functionalized nanoprobes for optimized nanomedicine.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 79 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all people
排除标准
- •patient under 18 years old, legal protection measure, pregnancy
结局指标
主要结局
impact of nanoparticles on coagulation tests ou platelet functions
时间窗: at the baseline
次要结局
- Difference of behaviour of the nanoparticles (N=10 preparations) on coagulation cascade and platelet functions(at the baseline)
研究者
研究点 (1)
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