Composite Autonomic Scoring Scale and HUTT to Assess Cardiac Autonomic Nervous Function: A Preliminary Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 169
- 试验地点
- 1
- 主要终点
- To find the indicators which are most correlated to the sympathetic and vagus nerves.
研究概览
简要总结
Autonomic nervous system diseases can cause abnormalities in the circulatory system, leading to malignant arrhythmia and sudden cardiac death. Standardized, operable, and simplified diagnostic indicators are urgently needed to evaluate autonomic nervous function, particularly cardiac autonomic nervous function. The investigators use HUTT in order to provide data support for cardiac autonomic nervous system evaluation.
详细描述
In this study, 169 samples with vertical tilt test and 24-h Holter ECG data from February 13, 2023 to October 31, 2023 were selected. The AC, DC, and 24-h HRV were compared with the CASS to identify the indicators with the strongest correlation with the CASS sympathetic and vagus nerve scores. The best index was selected, and the score intervals were delimited. The sensitivity and specificity of the defined vagal and sympathetic intervals were analyzed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 12 Years 至 85 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Vertical tilt test and 24-hour holter electrocardiogram were performed at the same time
- •Receive treatment in our hospital.
排除标准
- •Taking benzodiazepines or hypotensive drugs within 24 hours
- •Combined with mental illness, severe dementia, serious organ disease
- •Severe arrhythmia, deep breathing and poor coordination of Valsaval movements affected the interpretation of results.
结局指标
主要结局
To find the indicators which are most correlated to the sympathetic and vagus nerves.
时间窗: February 13, 2023 to December 31, 2025
The investigators use HUTT and CASS score to find some indicators which are most correlated to the sympathetic and vagus nerves,so that can give data support to the clinical treatments
次要结局
未报告次要终点
研究者
Yan Ding
Head of Neurology
The First Hospital of Hebei Medical University