NCT02433847Unknown4 期
Effect of Mosapride on Gut Transit in Patients With Chronic Constipation or Constipated Irritable Bowel Syndrome and Healthy Subjects
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 入组人数
- 20
- 主要终点
- colonic transit time
研究概览
简要总结
Effect of mosapride 30mg/day on the small bowel and colon transit time in patients with chronic constipation or constipated irritable bowel syndrome.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Functional constipation or constipated irritable bowel syndrome patients according to Rome III criteria
排除标准
- •Intolerable or hypersensitive to mosapride
- •Known Parkinson's ds
- •Cardio- or cerebrovascular disease within 3 months
- •Malignancy requiring surgery or chemotherapy or radiation within 5 years
- •History of GI surgeries except hernia repair, appendectomy, primary closure due to perforation
- •Refractory diabetes mellitus/hypertension/thyroid diseases
- •Symptomatic heart failure, renal failure, arrhythmia
研究组 & 干预措施
mosapride
Experimental
干预措施: Mosapride (Drug)
结局指标
主要结局
colonic transit time
时间窗: 2 weeks
the change of colonic transit time after mosapride 30mg/day administration : whole colonic transit time, rt. colon / lt. colon / rectosigmoid colonic transit time
次要结局
未报告次要终点
研究者
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