NCT02812134已完成不适用
Impact of Oral Phosphorus Supplements on the 6-month Change in FGF23 Levels in Anorexic Adolescents Suffering From Undernutrition.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- FGF23
研究概览
简要总结
Fibroblast growth factor 23 (FGF23) is a recently discovered phosphaturic hormone produced by osteocytes. It is involved in phosphate-calcium metabolism (via its phosphaturic action and inhibition of 1,25-OH vitamin D).
There are no published studies on the role of FGF23 in undernourished anorexic adolescents taking oral phosphorus supplements.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 11 Years 至 17 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adolescents aged from 11 to 17
- •Follow-up or hospitalisation for anorexia
- •Overt undernutrition (clinical signs of undernutrition, body mass index and the Waterlow index)
- •Social security coverage
排除标准
- •Known pre-existing renal disorders
- •Known constitutional disorders of phosphate-calcium metabolism
- •Adult patients, legal guardianship, incarceration
结局指标
主要结局
FGF23
时间窗: at inclusion and then once a month for 6 months.
Change in the FGF23 level (U/ml) with regard to the exogenous phosphorus intake (doses of Phosphoneuros®, expressed in mg/kg/day)
次要结局
未报告次要终点
研究者
研究点 (2)
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