A Randomized Open Controlled Clinical trial to evaluate the efficacy of trivrutta avaleha virechana followed by Putranjivak beeja churna in ksheena shukra w.s.r. (oligozoospermia)
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 68
- 试验地点
- 1
- 主要终点
- To evaluate the efficacy of trivrutta avaleha virechana followed by putranjivak beeja churna in ksheena shukra w.s.r. (oligozoospermia)
研究概览
简要总结
Oligozoospermia, or low sperm count, is a major contributing factor in male infertility and poses significant challenges to conception. Modern treatment options often involve costly, invasive, or temporary measures with limited holistic benefits. Ayurveda describes Ksheena Shukra as a condition comparable to oligozoospermia, caused by depletion or vitiation of Shukra Dhatu, and prescribes both Shodhana (purification) and Shamana (pacifying) therapies for its management.
This clinical trial is designed as a Randomized Open Controlled study to evaluate the efficacy of Trivrutta Avaleha Virechana (therapeutic purgation) followed by Putranjivak Beeja Churna (herbal seed powder) in patients with Ksheena Shukra (oligozoospermia). Virechana with Trivrutta Avaleha aims to eliminate accumulated doshas and enhance Agni and dhatu metabolism, thereby creating a favorable milieu for Shukra dhatu formation. Subsequent administration of Putranjivak Beeja Churna, known for its Vrushya (aphrodisiac), Balya (strength-promoting), and Garbhasthapaka (pro-natal) properties, is expected to nourish and restore Shukra Dhatu.
The study seeks to assess improvements in sperm count along with clinical outcomes. The results are anticipated to provide scientific validation for classical Ayurvedic therapies and establish an evidence-based, cost-effective, and non-invasive alternative for managing male infertility due to oligozoospermia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- Male
入选标准
- •Male patients aged between 20 and 50 years.
- •Diagnosed case of Oligozoospermia Sperm count less than 15 million/ml Male patients who have signed for consent form Male patients fit for virechana karma.
排除标准
- •Azoospermia.
- •Congenital disorders related to reproductive system like bilateral absence of the vas deferens, cryptorchidism, marfans syndrome, Klinefelter’s syndrome.
结局指标
主要结局
To evaluate the efficacy of trivrutta avaleha virechana followed by putranjivak beeja churna in ksheena shukra w.s.r. (oligozoospermia)
时间窗: 90 days
次要结局
- To compare the effect of trivrutta leha virechana followed by Putranjivak beeja churna over ashwatha phala churna in ksheena shukra (oligozoospermia)(90 days)
- To observe the efficacy of trivrutta leha virechana followed by Putranjivak beeja churna in ksheena shukra w.s.r. (oligozoospermia)(90 days)
- To achieve improvement in sperm count when given for 90 days.(90 days)
研究者
Bhushan Appasheb Kale
Department of PG studies in Prasuti tnatra and striroga, Yashwant Ayurvedic College A/p. Kodoli