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临床试验/NCT06973824
NCT06973824招募中不适用

A Twenty-years' Experience in Pituitary Disease: Identification of Prognostic Factors in Pituitary Tumors

Fondazione Policlinico Universitario Agostino Gemelli IRCCS1 个研究点 分布在 1 个国家目标入组 1,600 人开始时间: 2025年3月10日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
1,600
试验地点
1
主要终点
Tumor recurrence

研究概览

简要总结

Pituitary tumors represent a heterogeneous group of neoplasms by histotype. The pituitary adenomas are the most frequent heteroformation, among those affecting the pituitary gland, followed by meningiomas, craniopharyngiomas, germosomes and tumours secondary, such as metastases and lymphomas. Since these conditions are considered rare, the data epidemiology and prognosis to predict the natural history of these diseases can not be considered conclusive. Pituitary adenomas are a useful model for epidemiology in the study of pathology pituitary. Over the past 20 years, several attempts have been made to identify unique prognostic factors, which predict the outcome of these pathologies, but without To arrive at a definitive classification. The purpose of this study aims to collect clinical, biochemical, morphological and pathological data on the retrospective and prospective cohort of over 1600 patients undergoing neurosurgical removal of pituitary tumors in the last 20 years, to develop a prognostic classification.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Other

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients underwent surgery for pituitary tumors;
  • pathology diagnosis of pituitary tumors;
  • patients older then 18 years at diagnosis of pituitary tumors;
  • 2 years follow-up;

排除标准

  • age lower then 18 years
  • follow-up shorter than 2 years

结局指标

主要结局

Tumor recurrence

时间窗: From enrollement to last observation at 24 months of follow-up

Frequency of tumor recurrence at 24 months of follow-up

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Doglietto Francesco

Professor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

研究点 (1)

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A Twenty-years' Experience in Pituitary Disease. | 临床试验