A Twenty-years' Experience in Pituitary Disease: Identification of Prognostic Factors in Pituitary Tumors
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,600
- 试验地点
- 1
- 主要终点
- Tumor recurrence
研究概览
简要总结
Pituitary tumors represent a heterogeneous group of neoplasms by histotype. The pituitary adenomas are the most frequent heteroformation, among those affecting the pituitary gland, followed by meningiomas, craniopharyngiomas, germosomes and tumours secondary, such as metastases and lymphomas. Since these conditions are considered rare, the data epidemiology and prognosis to predict the natural history of these diseases can not be considered conclusive. Pituitary adenomas are a useful model for epidemiology in the study of pathology pituitary. Over the past 20 years, several attempts have been made to identify unique prognostic factors, which predict the outcome of these pathologies, but without To arrive at a definitive classification. The purpose of this study aims to collect clinical, biochemical, morphological and pathological data on the retrospective and prospective cohort of over 1600 patients undergoing neurosurgical removal of pituitary tumors in the last 20 years, to develop a prognostic classification.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients underwent surgery for pituitary tumors;
- •pathology diagnosis of pituitary tumors;
- •patients older then 18 years at diagnosis of pituitary tumors;
- •2 years follow-up;
排除标准
- •age lower then 18 years
- •follow-up shorter than 2 years
结局指标
主要结局
Tumor recurrence
时间窗: From enrollement to last observation at 24 months of follow-up
Frequency of tumor recurrence at 24 months of follow-up
次要结局
未报告次要终点
研究者
Doglietto Francesco
Professor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
