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临床试验/NCT01331382
NCT01331382已完成不适用

Effects of Resveratrol Alone or in Combination With Piperine on Cerebral Blood Flow Parameters and Cognitive Performance in Humans

Northumbria University2 个研究点 分布在 1 个国家目标入组 23 人开始时间: 2010年4月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
23
试验地点
2
主要终点
Modulation of levels of total haemoglobin

研究概览

简要总结

Resveratrol is associated with a plethora of physiological effects in humans, including modulation of cerebral blood flow, despite apparently poor bioavailability. This study investigated whether the physiological effects of resveratrol could be affected when co-supplemented with piperine, an alkaloid which may be able to enhance the bioavailability of resveratrol.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Between the ages of 18-35 years old
  • Non-smoker

排除标准

  • Not proficient in English
  • Taking medication or herbal supplements
  • Pregnant or breast feeding
  • Heavy caffeine consumer
  • History of head trauma, migraines, learning difficulties, ADHD, gastrointestinal problems.
  • Food allergies of intolerances

结局指标

主要结局

Modulation of levels of total haemoglobin

时间窗: 80 minutes following treatment administration

Modulation of levels of deoxygenated haemoglobin

时间窗: 80 minutes following treatment administration

Modulation of levels of oxygenated haemoglobin

时间窗: 80 minutes following treatment administration

次要结局

  • Number of participants displaying significant modulation of cognitive performance(40-80 minutes post dose)

研究者

申办方类型
Other

研究点 (2)

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