NCT07084194尚未招募不适用
Impact of Integrating Two Nano Based Irrigants With Two Activation Techniques in Treatment of Teeth With Acute Pulpitis on Postoperative Pain and Flare up Incidence: A Randomized Clinical Study
Minia University0 个研究点目标入组 64 人开始时间: 2025年9月10日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 64
- 主要终点
- postoperative pain intensity Postoperative pain is to be assessed using visual analog scale (VAS), A scale from (0 to 10) where "0" means no pain and "10 means a severe pain that has never faced before.
研究概览
简要总结
This study aimed to evaluate and compare impact of integrating passive ultrasonic activation and laser activation with nano-chitosan and aloe vera in terms of postoperative pain and flare-up incidence in a randomized clinical trial.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Participant)
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 18-60 (adults only)
- •multiple-rooted with multiple root canal.
- •Permanent teeth with mature apex and complete root formation.
- •Without root caries.
- •Tooth must be restorable.
- •Without anatomical abnormalities such as fusion.
- •Healthy patient category I according to ASA.
- •Vital tooth, with acute irreversible pulpitis and without peri-apical periodontitis.
- •No periapical radiolucency.
- •Consent Patients for who consent to participate and attend follow-up appointments.
排除标准
- •single root canals or double root.
- •Root canal calcifications.
- •Root resorption or fracture.
- •Previously root canal treated teeth.
- •immunocompromised patients.
- •Pregnant females
- •Patients with systemic diseases as diabetic or hypertension patients.
- •Patients with facial swelling.
- •patients who use analgesics or antibiotics within 48-72 hours.
- •Allergy to any materials used (e.g., irrigants or anesthetics).
- •psychiatric illness
- •Teeth that are not indicated for endodontic treatment: bad oral hygiene, mobile teeth, or recessed teeth.
- •Previously endodontically treated teeth.
- •Teeth with sinus tract.
结局指标
主要结局
postoperative pain intensity Postoperative pain is to be assessed using visual analog scale (VAS), A scale from (0 to 10) where "0" means no pain and "10 means a severe pain that has never faced before.
时间窗: [Time Frame: 6, 12, 24, 48, 72 hours and 7 days after the first visit to collect the postoperative pain data.]
Patients will be contacted by phone at 6, 12, 24, 48, 72 hours and 7 days after the first visit to collect the postoperative pain data.
次要结局
- Flare-Up Incidence Flare-up is assessed through asking the patient to notify the investigator if any sudden severe pain or swelling takes place.([Time Frame: Within 7 days post-treatment))
研究者
Rabee Ibrahaim Ismail Alhabibi
Rabee Alhabibi
Minia University
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