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临床试验/NCT07409688
NCT07409688招募中4 期

Comparative Evaluation of Analgesic Outcomes of Intra-peritoneal Versus Subcutaneous Infiltration of Bupivacaine for Laparoscopic Cholecystectomy Patients "

Rawalpindi Medical College1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2026年1月17日最近更新:
干预措施

试验速览

阶段
4 期
状态
招募中
发起方
入组人数
100
试验地点
1
主要终点
Post opestive pain score

研究概览

简要总结

Laparoscopic cholecystectomy involves removal of gallbladder through small incision ports resulting in faster recovery. Small incisions are less painful and hence local anesthesis administered can be effective for pain management. This local anesthetic can be administered either within abdominal cavity or at sit of small incisions.

详细描述

Laparoscopic cholecystectomy is a minimally invasive surgical procedure involving removal of the gallbladder through multiple small trocar incisions. Compared with open surgery, this approach is associated with reduced postoperative pain, shorter hospital stay, and faster recovery. Despite its minimally invasive nature, postoperative pain remains a significant concern, particularly at port sites and from intraperitoneal irritation. Local anesthetic techniques have been shown to contribute to multimodal analgesia in laparoscopic surgery. Local anesthetic agents may be administered either intraperitoneally or by infiltration at trocar insertion sites to reduce postoperative pain and opioid requirements. However, the optimal route of local anesthetic administration for effective postoperative analgesia following laparoscopic cholecystectomy remains uncertain, warranting further clinical evaluation.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
15 Years 至 60 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • ASA I and II

排除标准

  • Allergic to local anesthetic Open cholecystectomy History of chronic pain History of abdominal surgery

研究组 & 干预措施

Intraperitoneal local anesthetic administration

Experimental

干预措施: Intraoperitoneal local anesthetic administration (Drug)

Sub cutaneous local anesthetic administration

Active Comparator

干预措施: Sub cutaneous administration of local anesthetic (Drug)

结局指标

主要结局

Post opestive pain score

时间窗: This will be measured using Visual Analog score upon arrival at post anesthesia care unit labelled as Time 0 then at time intervals 3h,6h, 12h and 24 hours post operatively

Rescue analgesia demand

时间窗: This will be the number of patients requiring resuce analgesia in 24h post operative period. Rescue analgesia will be administered if VAS score >4

次要结局

未报告次要终点

研究者

发起方
Rawalpindi Medical College
申办方类型
Other
责任方
Principal Investigator
主要研究者

Nimrah Iqbal

Principal Investigator

Rawalpindi Medical College

研究点 (1)

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