Surgical Treatment for Long Bone Metastases With Intramedullary Nail or Endoprosthetic Reconstruction
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Clinical outcomes after treatment of long bone metastases with intramedullary nail versus endoprosthetic reconstruction
研究概览
简要总结
To provide treatment guidelines for patients with long bone metastatic disease based on observational study and to propose an algorithm to guide orthopedic surgeons in decision-making for these patient.
详细描述
The objectives of this study were to examine clinical outcomes after reconstruction with intramedullary fixation (IMN) or endoprosthetic reconstruction (EPR) with a specific focus on (1) the rate of complication or failure; (2) differences in complication rates by anatomic site; (3) functional results as assessed by the Musculoskeletal Tumor Society System (MSTS); (4) differences in complication rate between patients treated with INM versus EPR; and (5) differences in survival in patients with metastatic bone disease based on disease-specific, laboratory, and demographic information.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •bone metastases of the extremity
排除标准
- •bone metastases of the spine
结局指标
主要结局
Clinical outcomes after treatment of long bone metastases with intramedullary nail versus endoprosthetic reconstruction
时间窗: 1 year
The objectives of this study were to examine clinical outcomes after reconstruction with intramedullary nail versus endoprosthetic reconstruction with a specific focus on differences in complication rate between patients treated with intramedullary nail versus endoprosthetic reconstruction
次要结局
- Survival in patients undergoing surgery for metastatic bone disease(1 year)
研究者
Costantino Errani
MD, PhD
Istituto Ortopedico Rizzoli