Development and clinical application of treatment for seasonal allergic rhinitis symptom caused by salivary secretory type IgA production. - Development of mouthpiece for seasonal allergic rhinitis symptom

The symptoms of allergic rhinitis severity classification (from 0 to12 points) before and after mouthpiece attachment were significantly improved after the experimental group (before 9.7) (after 4.3), whereas the control group The salivary flow rate was measured as salivary secretion rate (micro g / min), and it was measured after the experimental group (0.6) before loading (after 1.0 +0.6), but the control group did not change (before 0.7) , (after 1.0)). As a result of multiple item saliva test, the mouthpiece of the experimental group An increase in acid buffering capacity was observed before and after mounting. As a result of measuring the salivary IgA concentration (micro g /ml), the experimental group (10.4) before the mouthpiece was attached was significantly reduced compared to the control group (19.2). The salivary IgA concentration after wearing the mouthpiece did not change in both the experimental group and the control group, but the salivary IgA secretion rate (micro g/ min) in the experimental group. Results: Rhinitis severity classification before and after NG was significantly improved before and after NG. As a result of measuring the saliva flow rate, it was significantly increased before and after NG. It was revealed that salivary IgA secretion concentration was significantly decreased in hay fever patients. Conclusion: NG used for dental care showed the possibility of alleviating symptoms of allergic rhinitis caused with pollinosis by increasing saliva amount and salivary IgA secretion rate.