ISRCTN67540073已完成未知
A multi-centre, randomised, double blind, placebo-controlled trial evaluating the effects of early administration of fibrinogen concentrate in adults with major traumatic haemorrhage.
HS Blood and Transplant (NHSBT)0 个研究点目标入组 48 人开始时间: 2015年8月6日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 48
研究概览
简要总结
2018 Results article in https://www.ncbi.nlm.nih.gov/pubmed/29914530 results 2017 Protocol article in https://doi.org/10.1186/s13063-017-1980-x (added 12/09/2023)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Written informed consent or agreement, or waiver of consent, is obtained before any study related activity
- •2. The participant is judged to be an adult (aged 16 years or over) and is affected by traumatic injury
- •3. The participant is deemed by the attending clinician to have ongoing active haemorrhage with shock
- •AND REQUIRES:
- •4. Activation of the local major haemorrhage protocol for management of severe blood loss and/or transfusion of emergency (Group O) red cells
排除标准
- •1. The participant has been transferred from another hospital
- •2. The trauma team leader deems the patient inappropriate for the trial i.e. injuries deemed to be incompatible with life
- •3. More than 3 hours have elapsed from the time of injury
- •4. The participant is pregnant
- •5. Severe isolated TBI or unsalvageable head injury
研究者
相似试验
已完成
2 期
Repurposing anti-TNF for treating Dupuytren’s diseaseDupuytren's disease of the handSkin and Connective Tissue DiseasesDupuytren's diseaseISRCTN27786905niversity of Oxford181
已完成
不适用
Managing Avascular Necrosis Treatments: an Investigational Study (MANTIS)Avascular necrosis of the hipMusculoskeletal DiseasesOsteonecrosisISRCTN14015902niversity of Oxford21
已完成
不适用
Randomised, multi-centre, double-blind, placebo-controlled trial of vitamin D supplementation in adult and adolescent patients with asthmaTopic: RespiratorySubtopic: Respiratory (all Subtopics)Disease: RespiratoryRespiratoryAsthmaISRCTN07270894Barts and The London NHS Trust (UK)250
已完成
3 期
Clinical study to assess the efficacy and safety of Silexan in patients with depressioMild to moderate major depressive episodeMental and Behavioural DisordersISRCTN36202964Dr Willmar Schwabe (Germany)577
已完成
不适用
A multicentre, randomized, double-blind, placebo-controlled, parallel-design trial of the efficacy and safety of subcutaneous tetrodotoxin (Tectin) for moderate to severe inadequately controlled cancer-related paiCancer- and cancer therapy-related painCancer painCancerISRCTN75684296Wex Pharmaceuticals Inc (Canada)82