Astigmatic Vector Analysis of Posterior Corneal Surface - a Comparison Among Healthy, Forme Fruste and Overt Keratoconus Corneas
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 698
- 试验地点
- 1
- 主要终点
- Astigmatism corneal vectors (based on keratometric readings at the three millimeter optical zones for both corneal surfaces).
研究概览
简要总结
The main purpose of this study is to determine new diagnostic criteria for an eye disease called keratoconus.
详细描述
Eyes of patients who distinctly present signs of keratoconus, for both eyes, at corneal tomography (an exam commonly used in such cases), and those who present such signs in only one eye were compared to eyes of unaffected patients. Several characteristics of anterior and posterior corneal astigmatism (special emphasis was given to the latter) were collectively assessed among all patients by a method referred to as vectorial analysis. Statistical tests were then performed, in an attempt to highlight differences among those three groups of patients and, eventually, define new diagnostic criteria.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Good-quality Scheimpflug scans (approved by the device in the ''Examination Quality Specification'').
排除标准
- •Previous eye surgery or trauma, and any sort of corneal scarring that might interfere with keratometric data acquisition.
结局指标
主要结局
Astigmatism corneal vectors (based on keratometric readings at the three millimeter optical zones for both corneal surfaces).
时间窗: Through study completion, an average of 6 months.
Corneal tomography at an Scheimpflug-based tomographer
次要结局
未报告次要终点
研究者
Giuliano de Oliveira Freitas, MD.
MD
University of Sao Paulo