Home-based Preoperative Exercise Training for Lung Cancer Patients Undergoing Surgery: A Feasibility Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Retention rate
研究概览
简要总结
Surgical resection is the only curative treatment in patients diagnosed with lung cancer, the most mortal type of malignancy globally. However, following lung cancer resection, patients experience a substantial deterioration in health-related quality of life and have an increased risk of developing pulmonary complications.
Although current clinical guidelines strongly recommend preoperative exercise training to improve clinical outcomes after lung cancer surgery, inaccessibility to facility-based exercise programs is a major barrier to routine participation, with patients indicating a strong preference to exercise in a home-based environment.
The primary purpose of the present study was to evaluate the feasibility of a home-based exercise program (HBEP) in lung cancer patients awaiting surgical treatment. The secondary purposes were to evaluate the safety of the HBEP and to explore exercise effects on patients' HRQOL and physical performance, either pre-and post-surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Scheduled for surgical treatment of suspected or confirmed lung cancer (clinical stage IIIA or less)
- •Waiting time for surgery of at least two weeks from baseline assessment
- •Medical clearance to exercise.
- •Signed informed consent prior to initiation of study-related procedures.
排除标准
- •Metastatic cancer
- •Presence of physical or mental disabilities that contraindicated exercise training or physical testing
- •Unable to communicate in Portuguese or English
- •Performing combined aerobic plus resistance training over the past month (self-reported ≥2 days a week, ≥30 minutes each session).
结局指标
主要结局
Retention rate
时间窗: Baseline to 4-5 weeks after surgery
Defined as the ratio of patients who completed the study to those who were recruited, expressed as a percentage
Exercise attendance rate
时间窗: Baseline to 2-3 days before surgery
Attendance rate will be defined as the ratio of total completed to planned exercise sessions, expressed as a percentage.
Recruitment rate
时间窗: Baseline
Defined as the ratio of recruited patients to those who were eligible, expressed as a percentage.
Exercise compliance rate
时间窗: Baseline to 2-3 days before surgery
Compliance rate will be defined as the ratio of total completed to planned training volume, expressed as a percentage.
次要结局
- Adverse events(Baseline to 2-3 days before surgery)
- Changes in health-related quality of life(Baseline to 4-5 weeks after surgery)
- Changes in exercise capacity(Baseline to 4-5 weeks after surgery.)
- Changes in handgrip strength(Baseline to 4-5 weeks after surgery)
- Changes in five times sit to stand test(Baseline to 4-5 weeks after surgery)
研究者
Pedro Machado
Principal Investigator
Instituto Politécnico de Leiria