Imaging of Electrical Properties by MRI: Investigation of Age-Related Changes
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 120
- 试验地点
- 2
- 主要终点
- Conductivity in S/m at the head level in subjects aged 6 to 12 years
研究概览
简要总结
The goal of this study is to build a database of personalized EP (Electrical Properties) maps (accounting for age, anatomical location, and tissue complexity), obtained via MRI, to improve electromagnetic safety assessments, especially in the context of MRI. The EP values derived from this study are expected to be more accurate than current literature values, leading to more realistic specific absorption rate (SAR) modeling and improved patient safety. To investigate age-related differences, the study will include three distinct age groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 6 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Person aged between 6 and 12, 20 and 40 years or aged 70 years and above
- •Person affiliated with a social security scheme or beneficiary of such a scheme
- •Person, or parent/legal guardian in the case of minors, who has received full information about the organization of the study and has signed the informed consent form
排除标准
- •Contraindication to undergoing an MRI examination or the presence of an MRI-incompatible medical device
- •Person presenting a pathology or tissue damage in the examined areas that may affect the measured MRI parameters
- •Pregnant woman, woman in labor, or breastfeeding mother
- •Person deprived of liberty by judicial or administrative decision, or persons undergoing psychiatric care
研究组 & 干预措施
Children between 6 and 12 years old
干预措施: Magnetic Resonance Imaging (MRI) examination (Device)
Adults between 20 and 40 years old
干预措施: Magnetic Resonance Imaging (MRI) examination (Device)
Adults aged 70 and above
干预措施: Magnetic Resonance Imaging (MRI) examination (Device)
结局指标
主要结局
Conductivity in S/m at the head level in subjects aged 6 to 12 years
时间窗: Baseline (J0)
Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 6 to 12 years
Conductivity in S/m at the head level in subjects aged 20 to 40 years
时间窗: Baseline (J0)
Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 20 to 40 years
Conductivity in S/m at the head level in subjects aged 70 and above
时间窗: Baseline (J0)
Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 70 and above
Conductivity in S/m at the neck level in subjects aged 6 to 12 years
时间窗: Baseline (J0)
Measurement of conductivity (in Siemens per meter, S/m) at the neck level in subjects aged 6 to 12 years
Conductivity in S/m at the neck level in subjects aged 20 to 40 years
时间窗: Baseline (J0)
Measurement of conductivity (in Siemens per meter, S/m) at the neck level in subjects aged 20 to 40 years
Conductivity in S/m at the neck level in subjects aged 70 and above
时间窗: Baseline (J0)
Measurement of conductivity (in Siemens per meter, S/m) at the neck level in subjects aged 70 and above
Conductivity in S/m at the torso level in subjects aged 6 to 12 years
时间窗: Baseline (J0)
Measurement of conductivity (in Siemens per meter, S/m) at the torso level in subjects aged 6 to 12 years
Conductivity in S/m at the torso level in subjects aged 20 to 40 years
时间窗: Baseline (J0)
Measurement of conductivity (in Siemens per meter, S/m) at the torso level in subjects aged 20 to 40 years
Conductivity in S/m at the torso level in subjects aged 70 and above
时间窗: Baseline (J0)
Measurement of conductivity (in Siemens per meter, S/m) at the torso level in subjects aged 70 and above
次要结局
未报告次要终点
研究者
BRAUN Marc
Principal Investigator
Central Hospital, Nancy, France