NCT03591913已完成4 期
Comparison Between Preoperative and Postoperative Sublingual Misoprostol for Prevention of Postpartum Blood Loss in Cesarean Section : a Randomized Clinical Trial
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- mean intraoperative blood loss
研究概览
简要总结
Cesarean section is one of the most common major surgical operations among women. In 2015, the incidence of cesarean section in Woman Health Hospital in Assiut University accounts for 51.3 % of all deliveries
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •All pregnant women who will undergo elective lower segment cesarean section
- •term ( ≥ 37 weeks)
- •normal fetal heart tracing.
排除标准
- •Placenta previa-Rupture uterus
- •Classical cesarean section
- •Preterm delivery
- •Hypertensive disorders of pregnancy
- •Bleeding tendency
- •Previous history of postpartum hemorrhage
- •Concurrent anticoagulant therapy
- •Concurrent long-term use of steroids
- •Fetal distress
- •Antepartum haemorrhage
研究组 & 干预措施
study group
Experimental
will receive sublingual misoprostol immediately after urinary catheterization and before skin incision
干预措施: Misoprostol (Drug)
control group
Active Comparator
will receive sublingual misoprostol immediately after skin closure
干预措施: Misoprostol (Drug)
结局指标
主要结局
mean intraoperative blood loss
时间窗: 24 hours
Blood loss estimation will commence immediately following the skin incision
次要结局
未报告次要终点
研究者
Ahmed Mohamed Abbas
Principal investigator
Assiut University
研究点 (1)
Loading locations...
相似试验
招募中
4 期
Pre Versus Post-operative Misoprostol in Reducing Blood Loss After Cesarean SectionMisoprostol AllergyNCT05928871Cairo University120
尚未招募
3 期
Comparison Between Preoperative Vaginal and Postoperative Sublingual Misoprostol for Prevention of Postpartum Hemorrhage During Cesarean SectionPostpartum HemorrhageNCT06765473Assiut University400
已完成
不适用
Comparative Study Between Preoperative and Postoperative Rectal MisoprostolBlood Loss, SurgicalBlood Loss, PostoperativeNCT06049160Egymedicalpedia128
尚未招募
不适用
Comparison of Transversalis Fascia Plane Block and Erector Spinae Plane Blocks in Cesarean SectionPainPostoperative PainNCT05117307Erzurum Regional Training & Research Hospital60
已完成
不适用
Perinatal Morbidity Factors During Cesarean SectionPerinatal MorbidityNCT03928795University Tunis El Manar100