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临床试验/NL-OMON53083
NL-OMON53083招募中不适用

Detection Of Latent Pulmonary Hypertension In Genetically Susceptible Individuals. - DOLPHIN-GENESIS

Vrije Universiteit Medisch Centrum0 个研究点目标入组 140 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
140

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
16 至 64(—)

入选标准

  • 1. Diagnosis of idiopathic PAH, according to ESC/ERS guidelines (ref: Galie ERJ
  • Unaffected BMPR2 or other mutation carrier or other mutations associated with
  • Healthy relative of heritable PAH patient not carrying the disease causing
  • 2. Age >18 and <80 years
  • 3. Able to understand and willing to sign the Informed Consent Form

排除标准

  • - Pregnant subjects
  • - Claustrophobia
  • - Inability to provide informed consent
  • - In case of PAH patients: TLC < 70%pred or radiographic evidence of
  • interstitial lung disease
  • - In case of BMPR2 mutation carriers and family control subjects, one or more
  • of the following: abnormal spirometry, TLC < 70%, echocardiographic evidence of
  • pulmonary hypertension

研究者

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