The effect of perioperative intravenous lignocaine on pain outcomes at operative gynaecological laparoscopy in women with chronic pelvic pain, a randomised controlled trial.

Monash health0 个研究点目标入组 70 人开始时间: 2021年5月18日最近更新: 2023年4月10日

试验速览

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•Women requiring elective operative gynaecological laparoscopy for benign indication as determined and agreed by both the surgeon and the participant.
•- Experience of pelvic pain on most days in the preceding 6 months
•- Over 18years old and premenopausal at the time of the surgery.
•- Participants who understand the conditions of the study and are willing to participate for the duration of study including all follow-up.
•- Participants who are capable of, and have given, informed consent to their participation in the study.
•- English language or an available translator sufficient to complete the validated quality of life instruments.
•- Surgery at Moorabbin Hospital under specialised Endosurgery unit

•- Contraindications to lignocaine (Hypersensitivity; Myasthenia gravis; Severe shock; Supraventricular arrhythmia; Impaired cardiac conduction; Stokes-Adams syndrome or severe degrees of sinoatrial, atrioventricular or intraventricular heart block unless the participant has an artificial pacemaker; Severe renal or liver disease; Use of beta blocker medication e.g. propranolol, metoprolol, atenolol, bisoprolol; Use of Anti-arrhythmic medication e.g. amiodarone, flecainide sotalol, digoxin; Electrolyte abnormalities)
•- No significant and persisting pain component to presentation in preceding 6 months.
•- Known or suspected malignancy
•- Pregnancy
•- Requirement for alternative analgesia regimen
•- Current/recent use of methadone within 6months of surgery

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