NCT02844686Unknown不适用
Feasibility of Dynamic Cardiac SPECT With 99mTc-diethylenetriaminepenta-acetate (DTPA) for the Assessment of Myocardial Flow Reserve Using a Cadmium-Zinc-Telluride (CZT) Camera
适应症
干预措施
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 主要终点
- Feasibility of myocardial flow reserve assessment by dynamic cardiac SPECT using a CZT camera and 99mTc-DTPA
研究概览
简要总结
New CZT-based SPECT cameras are potentially capable of dynamic 3-D acquisition. Preliminary results suggested that dynamic acquisitions could allow the assessment of myocardial flow reserve using 99mTc-labelled perfusion tracers. The Flow-Heart study will assess the feasibility of myocardial flow reserve measurement by means of 99mTc-DTPA dynamic cardiac SPECT in 20 patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age over 18 years
- •Patient clinically stable with known or suspected coronary disease
- •Patient referred to Caen University Hospital for a myocardial perfusion SPECT
- •Patient who accept to undergo subsequent additional cardiac dynamic SPECT using 99mTc-DTPA at rest and during pharmacological stress
- •Informed consent dated and signed
- •Affiliation to a social security system
排除标准
- •Contraindication to dipyridamole (asthma, chronic obstructive pulmonary disease , pulmonary hypertension)
- •History of poor tolerance of dipyridamole injection
- •Cardiac arrhythmia (atrial fibrillation or frequent premature ventricular complex)
- •Left bundle branch block, cardiac pacemaker, or implantable automatic defibrillator
- •Recent history of myocardial infarction or unstable angina
- •Pregnancy or lactating women
- •Known obstructive renal or urinary disease
- •Age under 18 years or guardianship
- •Patient with an acute coronary syndrome or a coronary revascularization occurring between the conventional perfusion SPECT and the subsequent 99mTc-DTPA dynamic SPECT
研究组 & 干预措施
Cardiac Dynamic SPECT
Experimental
干预措施: Cardiac SPECT (Other)
结局指标
主要结局
Feasibility of myocardial flow reserve assessment by dynamic cardiac SPECT using a CZT camera and 99mTc-DTPA
时间窗: Within one month after a conventional myocardial perfusion SPECT
次要结局
未报告次要终点
研究者
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