NCT00765687已完成4 期
A Multi-center Observational Clinical Study of Screening of Non-small-cell Lung Cancer With Bone Metastasis and Efficacy and Safety of Those Receiving Bisphosphonates
Sun Yat-sen University1 个研究点 分布在 1 个国家目标入组 432 人开始时间: 2008年8月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 432
- 试验地点
- 1
- 主要终点
- Skeleton-related event
研究概览
简要总结
A multicenter Prospective Study to assess the screening methods, parameter of NTX and the efficacy and safety of zoledronic acid treatment in addition to anti-tumor therapy in patients of non-small cell cancer with bone metastasis in china.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age >18, either sex
- •Histologically confirmed non-small cell cancer
- •One bone metastasis at least confirmed by image(X ray,CT or others)
- •Without receiving zoledronic acid
- •Life expectancy > 6 M
排除标准
- •Women who are pregnant or in lactation
- •Patients with hyperostosis
- •with brain metastasis(exception of those without symptom or with Metastasis Lesions under controlled
- •Previous or current treatment with any other bisphosphonates, bone- protecting, cytotoxic or targeted therapy
- •Severe co-morbidity of any type that may interfere with assessment of the patient for the study -
研究组 & 干预措施
Observation
No Intervention
干预措施: bisphosphates (Drug)
结局指标
主要结局
Skeleton-related event
时间窗: 24 months
次要结局
- overall survival(24 months)
研究者
Li Zhang
Profressor
Sun Yat-sen University
研究点 (1)
Loading locations...
相似试验
Unknown
不适用
Diagnosing Bacterial Vaginosis/Vaginitis (BV) Using the Gynecologene Test MethodVaginosis, BacterialNCT02558179American International Biotechnology300
尚未招募
不适用
A multicenter prospective clinical study for the treatment of spleen and kidney insufficiency metrorrhagia and metrostaxis with Lingnan Hemostatic Prescription Erren DecoctioITMCTR1900002640The First Affiliated Hospital of Guangzhou University of Chinese Medicine
已完成
不适用
Performance and Safety Use of the Nanostructured Titanium Dental Implant "KONTACT N"Dental ImplantDental RestorationEdentulous Alveolar RidgeImplant-supported Fixed ProsthesisNCT03582657Biotech Dental164
已完成
不适用
An Observational Study of Pegasys (Peginterferon Alfa-2a) in Chinese Patients With HBeAg Negative Chronic Hepatitis BHepatitis B, ChronicNCT01730508Hoffmann-La Roche978
已完成
不适用
An Observational Study of Induction Therapy With Fuzeon (Enfuvirtide) in Combination With Antiretroviral Drugs in Patients With HIV-1 InfectionHIV InfectionsNCT01902615Hoffmann-La Roche58