Blood Pressure and Cardiac Autonomic Adaptations to Isometric Exercise Training: a Randomised Sham-controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Blood pressure (systolic, diastolic and mean BP)
研究概览
简要总结
A randomized, sham-controlled intervention measuring the effects of isometric exercise training (IET) on blood pressure and cardiac autonomics.
IET has been proven effective in a plethora of randomized trials, but very little research has employed a sham-controlled design. This researched involved the recruitment of 30 participants who completed a 4 week IET intervention, sham control of the IET intervention, or a non-intervention control period. Pre and post blood pressure and cardiac autonomic measures were acquired and analysed.
The hypothesis of this trial was a significant effect of IET on blood pressure, with no such effects following the sham control or normal control interventions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
盲法说明
Participants in the sham intervention group were not aware they they were not performing the IET intervention.
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy with no significant health conditions contraindicating exercise
- •Over 18 years of age
- •Physically inactive
排除标准
- •Achieving current physical activity guidelines
- •Abnormal resting ECG
研究组 & 干预措施
No intervention control
Participants allocated to this arm did not perform any exercise and were required to maintain usual daily habits.
IET
Participants allocated to this arm performed 4 weeks of isometric wall squat exercise training, 3 times per week.
干预措施: Isometric exercise training (Other)
Sham
Participants allocated to this arm performed 4 weeks of isometric wall squat training, but the training prescription was intentionally provided at an insufficient intensity to achieve any physiology stimulus.
干预措施: Isometric exercise training (Other)
结局指标
主要结局
Blood pressure (systolic, diastolic and mean BP)
时间窗: At the end of the intervention (post 4 weeks)
Resting office blood pressure measured at brachial artery
Cardiac autonomics measured at HRV
时间窗: At the end of the intervention (post 4 weeks)
LF and HF power spectral measures
Blood pressure (systolic, diastolic and mean BP)
时间窗: At the start of the intervention (pre 4 week intervention)
Resting office blood pressure measured at brachial artery
Cardiac autonomics measured at HRV
时间窗: At the start of the intervention (pre 4 week intervention)
LF and HF power spectral measures
次要结局
- continuous 5-minute blood pressure (systolic, diastolic and mean BP)(At the end of the intervention (post 4 weeks))
- continuous 5-minute blood pressure (systolic, diastolic and mean BP)(At the start of the intervention (pre 4 week intervention))