跳至主要内容
临床试验/NCT03472066
NCT03472066已完成不适用

Measurement of the Cervix During Pregnancy According to Age of Conization

Centre Hospitalier Universitaire, Amiens1 个研究点 分布在 1 个国家目标入组 2 人开始时间: 2018年10月4日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
2
试验地点
1
主要终点
The main objective is to study the correlation between the size of the cervix and the age at conization. age at conization

研究概览

简要总结

Treatment of precancerous lesions of the cervix by conization has been shown to increase the risk of premature delivery and premature rupture of the membranes. It has now been clearly established that the cervix is a growing organ during adolescence and early adulthood, It has been hypothetized that cervical conization during the growth phase reduced its growth potential, and induced shorter cervix during the upcoming pregnancy. No studies have been conducted investigating the age at which conization no longer had an impact on cervical size during pregnancy. This will help to identify the age at conisation below which patients will be identified as being at risk event, and thus offer increased monitoring and possibly prophylactic management by programmed strapping. We propose to measure the length of the cervix of pregnant patients who have benefited from conization, which is currently recommended by the Collège National des Gynécologues Obstetriciens Français .In addition, the investigators will use a control group consisting of non-con conical, parity-matched pregnant patients in whom a cervical measurement will also be performed.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
Female
接受健康志愿者
否

入选标准

  • •Patient referred since January 2008 with pregnancy between 2008 and 2017
  • •Pregnancy after conisation
  • •Cervix size between 21 and 24 SA before any obstetric event
  • •Control group: parity matching, asymptomatic patients

排除标准

  • •Threat of late miscarriage,
  • •Premature rupture of membranes before cervical echography,
  • •Other pregnancies after study of 1st pregnancy after conisation,
  • •No measurement of the conization specimen,
  • •Lost to follow-up,
  • •Twin Pregnancies
  • •Patient under guardianship

研究组 & 干预措施

a group of women who have been conized

Previous conization

干预措施: Previous conization (Other)

control group with asymptomatic patients

on routine second trim no previous conization

干预措施: no previous conization (Other)

结局指标

主要结局

The main objective is to study the correlation between the size of the cervix and the age at conization. age at conization

时间窗: 1 day

Cervix length Measured during the second semester echography

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验