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临床试验/NCT01239524
NCT01239524已完成3 期

The Significance of Latissimus Dorsi Flap Innervation in Delayed Breast Reconstruction

Tampere University Hospital0 个研究点目标入组 28 人开始时间: 2010年11月11日最近更新:
适应症

试验速览

阶段
3 期
状态
已完成
入组人数
28

研究概览

简要总结

Breast reconstruction with a pedicled myocutaneous latissimus dorsi (LD) flap is a widely used reconstruction method. It is controversial if surgical denervation by transecting the thoracodorsal nerve should be performed or not. It is assumed that after denervation the latissimus dorsi muscle will significantly atrophy and lose volume. On the other hand discomforting signs and symptoms from muscle contraction are believed to be prevented if flap is denervated. The aim of the study was prospectively evaluate the influence of LD-flap innervation on the functional and aesthetic outcome of delayed breast reconstruction, and to compare the change in muscle structure in breast MRI and histopathology.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
20 Years 至 70 Years(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • delayed LD-flap breast reconstruction, no recurrent disease observed

排除标准

  • recurrent cancer, partial resection of the breast

研究者

申办方类型
Other

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