Are elevated prolactin levels harmful for the retinal and sublingual microvascular bed? - Prolactin and the retinal and sublingual microvascular bed.

Academisch Medisch Centrum0 个研究点目标入组 20 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

暂无简介。

•(For both patients as controls, with obviously exception of the first inclusion criteria)
•Patients (both women and men) with active prolactinoma (either micro- or macroprolactinoma, with prolactin levels above >50 ng/ml
•Age 20-60 years.
•Written informed consent

•(For both patients as controls)
•Macroprolactinemie.
•Infundibulum infiltration.
•Diabetes mellitus type 2.
•Pregnant women.
•Premature atherosclerosis.
•Use of antidepressive and antipsychotic medication.
•Presence of co-morbidity that could affect retinal vasculature or its matrix.
•History of hypersensitivity or allergy to fluorescein.
•Inability to obtain SDF, fluorescein angiograms or OCT*s of sufficient quality to be analyzed and graded.
•Active malignancy.
•Systemic disease with a life expectancy shorter than the duration of the study.
•Inability to adhere to the protocol with regard to injection and visits.
•Legally incompetent adult.
•Refusal to give written informed consent.
•Additional use of medication that could affect neo-angiogenesis.

发起方