Effect of diacerein on renal function, metabolic control and acute inflamatory parameters in type 2 diabetic patients with nephropaty - randomized clinical trial - : Diacereina trial on diabetes mellitus with nephropaty

niversidade Federal do Rio Grande do Sul0 个研究点开始时间: 2016年11月7日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•Patients from 30 to 80 years old, with type 2 diabetic with microalbuminuria. macroalbuniria and or diminished glomerular filtration rate (GFR - stages 1 and 2); HbA1c from 7.5 to 10%; in regular use of inhibitor Angiotensin Converting Enzyme or Angiotensin Receptor Blocker; Body mass index bellow 40kg / m²; do not make use of pioglitazone; Use of antihyperglycemic medications; Acceptance to participate and to sign informed consent; Patients seen in the outpatient medical clinic of the Faculdade de Medicina of Universidade de Passo Fundo

•Pregnant and lactating women; presence of chronic inflammatory diseases such as arthritis, colitis; Infectious Disease like tuberculosis; use of anti-inflammatory drugs for more than five days in the last three months; previous diagnosis of pancreatitis; hypersensitivity to reigns or its correlates (laxative); Smoking; severe liver disease (transaminases major than 2.5 times the upper limit of normal); severe gastrointestinal disease; participation in another trial in the past 30 days; failure to follow the research protocol requirements

发起方

niversidade Federal do Rio Grande do Sul